Jessica Pepin, Nurse Practitioner

Jessica Pepin is a dedicated psychiatric nurse practitioner who provides compassionate, evidence-based medication management to adults across Massachusetts. At LifeStance Health, she supports patients aged 18 through 40 with a collaborative approach that prioritizes safety, trust, and long-term well-being. Jessica works closely with each individual to understand their symptoms, treatment goals, and daily challenges, ensuring that every care plan is tailored to meet their unique needs. Jessica is especially passionate about helping individuals manage the complex intersection of PTSD and substance use. She brings a deep understanding of how trauma can influence coping behaviors, emotional regulation, and overall mental health. Her approach incorporates trauma-informed care and emphasizes restoring balance through individualized medication management and thoughtful integration of therapeutic interventions. Whether addressing early recovery needs or supporting long-term sobriety, Jessica strives to help patients build resilience, regain stability, and move toward lasting recovery. With clinical experience treating depression, anxiety, bipolar disorder, and sleep disturbances, Jessica combines pharmacological expertise with interventions such as Cognitive Behavioral Therapy (CBT), Dialectical Behavior Therapy (DBT), and mindfulness-based strategies. She also supports LGBTQ+ individuals with affirming care that acknowledges and respects the impact of identity on mental health. Additional areas of clinical focus include health psychology and women’s mental health. Outside of her work, Jessica enjoys hiking the beautiful landscapes of New England and spending quiet time reading. Her practice in Massachusetts is rooted in empathy, clinical integrity, and a genuine commitment to helping patients live fuller, more stable lives.